![]() If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.Ĭonditions which augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings. Some of the topical corticosteroids and their metabolites are also excreted into the bile. Corticosteriods are metabolized primarily in the liver and are then excreted by the kidneys. Corticosteroids are bound to plasma proteins in varying degrees. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses (see DOSAGE AND ADMINISTRATION). Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Topical corticosteroids can be absorbed from normal intact skin. Consult your doctor before breast-feeding.The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. Other medications in this class pass into breast milk when taken by mouth. It is unknown if this drug passes into breast milk when applied to the skin. Discuss the risks and benefits with your doctor. See the doctor regularly so your child's height can be checked.ĭuring pregnancy, this medication should be used only when clearly needed. Though it is unlikely, this medication may temporarily slow down a child's growth if used for a long time. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months. Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Talk to your pharmacist for more details.īefore using this medication, tell your doctor or pharmacist your medical history, especially of:ĭo not use if there is an infection or sore present in the area to be treated. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Precautionsīefore using triamcinolone, tell your doctor or pharmacist if you are allergic to it or to other corticosteroids (such as hydrocortisone, prednisone) or if you have any other allergies. You may report side effects to Health Canada at 1-86. ![]() You may report side effects to FDA at 1-80 or at In Canada - Call your doctor for medical advice about side effects. If you notice other effects not listed above, contact your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. This is not a complete list of possible side effects. itching/swelling (especially of the face/tongue/throat).However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: Tell your doctor right away if any of the following side effects occur:Ī very serious allergic reaction to this drug is rare. These side effects are more likely in children, and in people who use this medication for a long time or over large areas of the skin. This can lead to side effects of too much corticosteroid. Rarely, it is possible this medication will be absorbed from the skin into the bloodstream. Notify your doctor if redness, swelling, or irritation do not improve. Skin infections can become worse when this medication is used. small red bumps on the skin (folliculitis).Tell your doctor right away if you have any serious side effects, including: Many people using this medication do not have serious side effects. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. If any of these effects last or get worse, notify your doctor or pharmacist promptly. This should disappear in a few days as your body adjusts to the medication. Burning, itching, irritation, or dryness may occur when this medication is first applied to the skin.
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